PATHOPHYSIOLOGY P D

Parkinson's Disease Pathophysiology: Loss of dopaminergic neurons in substantia nigra that project to striatum leading to loss of dopamine in caudate and putamen that results in classical triad of Parkinson's i.e. tremors,rigidity and bradykinesia

Pathology of Parkinson's extends beyond basal ganglia and dopamine and affect other parts and neuro transmitters of the brain Serotonin ( Raphae Nuclei) Acetyl Choline ( Pedunculo- Pontine Nucleus) Nor Epinephrine (Locus ceruleus) #humsaathhai #DBLsocialwelfarefoundation #PhysiodeptGHMC